Superoxide Dismutase Activity in Leukocytes

Superoxide dismutase activity in leukocytes.

Superoxide dismutase activity has been identified in both human neutrophils and rabbit alveolar macrophages by two distinct assay procedures. The enzyme is insensitive to both cyanide and azide and is present in the cytosol of the cell. The identification of this enzyme in phagocytic cells is compatible with the theory that superoxide anion might be involved in the bactericidal activity of the ...

Superoxide dismutase Superoxide dismutase

the plasma antioxidant activity of superoxide dismutase enzyme in osteoporosis

osteoporosis is a metabolic disease characterized by reduction in bone density and susceptibility to deformity and fracture. some studies show that osteoblasts can create inter-cellular free radicals that lead to cellular death. superoxide dismutase (sod) plays an essential role in cell defense against reactive oxygen metabolites. the purpose of this study was to measure the plasma sod activiti...

Salivary superoxide dismutase activity in the consumers of paan containing tobacco

Introduction:The habit of smokeless tobacco chewing is one of the known risk factors for oral cancer among the residents of southeast of Iran. Most likely, the antioxidant defense system in dealing with free radicals induced paan and prevention of oral cancer is important. In this study, the activity of superoxide dismutase is compared in the saliva of paan consumers and non-consumers. Metho...

Gene transfer of extracellular superoxide dismutase increases superoxide dismutase activity in cerebrospinal fluid.

BACKGROUND AND PURPOSE Copper-zinc superoxide dismutase (CuZnSOD) is expressed intracellularly, while extracellular SOD (EC-SOD) is released from cells. The purpose of this study was to determine whether gene transfer of CuZnSOD increases SOD activity predominantly in tissues, and gene transfer of EC-SOD increases SOD activity in cerebrospinal fluid (CSF). We also determined whether heparin or ...